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【产品介绍】ADORA1 is an adenosine receptor that belongs to the G-protein coupled receptor 1 family. There are 3 types of adenosine receptors, each with a specific pattern of ligand binding and tissue distribution, and together they regulate a diverse set of physiologic functions. The type A1 receptors inhibit adenylyl cyclase, and play a role in the fertilization process. Animal studies also suggest a role for A1 receptors in kidney function and ethanol intoxication (1). Recommended Applications
WB, IHC, ICC, IP, FC Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000 IHC: 1:100 - 250 ICC: 1:50 - 100 IP: 1:10 - 100 FC: 1:100 - 500 Species Reactivity * Human *Species cross-reactivity is based on WB analysis. Products Data Western blot analysis on (A) Saos-2, (B) SH-SY5Y, (C) Caco-2, (D) A549, and (E) 293T cell lysates using anti-ADORA1 RabMAb (cat. #5358-1). Immunohistochemical analysis of paraffin-embedded human breast tissue using anti-ADORA1 RabMAb (cat. #5358-1). Specificity A synthetic peptide corresponding to residues in the extracellular domain in human ADORA1 was used as an immunogen. |