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【产品介绍】ADORA1 is an adenosine receptor that belongs
to the G-protein coupled receptor 1 family. There are
3 types of adenosine receptors, each with a specific
pattern of ligand binding and tissue distribution,
and together they regulate a diverse set of
physiologic functions. The type A1 receptors
inhibit adenylyl cyclase, and play a role in
the fertilization process. Animal studies also suggest
a role for A1 receptors in kidney function and
ethanol intoxication (1).
Recommended Applications
WB, IHC, ICC, IP, FC
Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000
IHC: 1:100 - 250
ICC: 1:50 - 100
IP: 1:10 - 100
FC: 1:100 - 500
Species Reactivity * Human *Species cross-reactivity is based on WB analysis. Products Data
Western blot analysis on (A) Saos-2, (B) SH-SY5Y,
(C) Caco-2, (D) A549, and (E) 293T cell lysates
using anti-ADORA1 RabMAb (cat. #5358-1).
Immunohistochemical analysis of paraffin-embedded
human breast tissue using anti-ADORA1 RabMAb (cat. #5358-1). Specificity A synthetic peptide corresponding to residues in
the extracellular domain in human ADORA1 was used
as an immunogen. |
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