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生化科研试剂 >> 抗体产品 >> 内参抗体 |
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Alpha-Actinin 2 Alpha-Actinin 2 |
别 名: |
ACTN2, Alpha-actinin-2, Alpha-actinin skeletal muscle isoform 2;F-actin cross-linking protein |
货号 |
品名 |
规格 |
包装 |
单价 |
货期 |
库存 |
1227178918 |
Alpha-Actinin 2 |
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100ul |
3575元 |
现货 |
3天 |
提示信息:偏远地区如新疆西藏宁夏甘肃等地可能无法运送液体,下单前请联系客服。 |
性 状: |
【产品类型】Rabbit Monoclonal IgG 【反应特异性】Human , Mouse , Rat 【克隆 ID】EP2530Y 【用途】WB , IHC , IP 【产品性状】 【阳性对照】 【产品浓度】 【细胞定位】 【抗原分子量】100 kDa |
质量标准: |
【产品介绍】Alpha-actinin is a ubiquitously expressed protein found in numerous actin structures. It consists of an N-terminal actin binding domain, a central rod domain, a n d a C-terminal domain a n d functions as a homodimer to cross-link actin filaments. The rod domain determines the distance between cross-linked actin filaments a n d also serves as an interaction site f o r several cytoskeletal a n d signaling proteins (1). Alpha-actinins are a multigene family of four actin-binding proteins related to dystrophin. The two skeletal muscle isof o r ms of alpha-actinin (ACTN2 a n d ACTN3) are maj o r structural components of the Z-line involved in anch o r ing the actin-containing thin filaments. In humans, ACTN2 is expressed in all muscle fibers, while ACTN3 expression is restricted to a subset of type 2 fibers (2).Recommended Applications WB, IHC, IP Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000 IHC: 1:100 - 250 IP: 1:40 Species Reactivity * Human, Mouse, Rat * *Cross reactivity determined by western blot only. Products Data A. Western blot analysis on human skeletal muscle lysate using anti-Alpha-Actinin 2 RabMAb (cat. # 2340-1), dilution 1:50,000 B. Immunohistochemical analysis of paraffin-embedded human muscles using anti-Actinin 2 RabMAb (cat. #2340-1). Specificity A synthetic peptide corresponding to residues near the C-terminus of human Alpha-Actinin 2 was used as an immunogen. |
贮 存: |
50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
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