Recombinant Human Fibroblast Growth Factor 8 是胚胎发育过程中的一个重要因子,参与前列腺癌的进展。 Synonyms rHuFGF-8; FGF-8; AIGF; HBGF-8 ; 重组人成纤维细胞生长因子 8 Species HumanSource E. coli Accession P55075 Gene ID 2253 Molecular Weight Approximately 22.5 kDa AA Sequence MQVTVQSSPN FTQHVREQSL VTDQLSRRLI RTYQLYSRTS GKHVQVLANK RINAMAEDGD PFAKLIVETD TFGSRVRVRG AETGLYICMN KKGKLIAKSN GKGKDCVFTE IVLENNYTAL QNAKYEGWYM AFTRKGRPRK GSKTRQHQRE VHFMKRLPRG HHTTEQSLRF EFLNYPPFTR SLRGSQRTWA PEPR Biological Activity The ED50 is <5 ng/mL as measured by TF-1 cells, corresponding to a specific activity of >2 × 105 units/mg. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS. Endotoxin Level <0.2 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Human Fibroblast Growth Factor 8 (rHuFGF-8) to 100 µg/mL using ddH2O. Storage & Stability Lyophilized recombinant Human Fibroblast Growth Factor 8 (rHuFGF-8) is stored at -20°C. After reconstitution, it is stable at 4°C for 2 weeks or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background Fibroblast Growth Factor 8 is an essential factor during embryonic development, overexpressed in several tumor types. Fibroblast Growth Factor 8 stimulates anti-apoptotic pathways and prevents tumor cell death[1]. |